Dowling Group

Welcome to the Dowling Group.

We primarily use X-ray crystallography and biochemical techniques to study the structure and function of important biological systems. Our research focuses include: Challenging chemistry in natural product biosynthesis (currently focusing on azoline formation), enzymes that modify biomolecules (such as DNA and RNA modification enzymes), two component flavin monooxygenases involved in breaking C-S bonds, and protein-DNA complexes (such as transcription regulators).

We are located in the Integrated Science Complex!

Protein Structure

 

Lab Picture

Lab News!

Congratulations to undergraduate lab members Alice Wong and AudreyAnn Supreme for receiving CSM Undergraduate Research Fellowship Awards!       09/2021    

I am excited to share that my tenure package has officially been accepted, and I can't wait to see what the future brings for the lab! Thank you to all current and past members of the Dowling Lab whose hard work, enthusiasm, and scientific creativity helped establish our lab!     06/2021

Congratulations to undergraduate lab members Simon Johnson, Courtney Truong, Israa El Saudi, and Clara Barthelemy for graduating in May 2020!    

Congratulations to graduate student Jeremy Liew, undergraduate student Israa El Saudi, and our collaborators for an accepted article at JBC entitled Structures of the alkanesulfonate monooxygenase MsuD provide insight into C–S bond cleavage, substrate scope, and an unexpected role for the tetramer!     05/2021 

Congratulations to undergraduate Biochemistry Major Catherine Gaitanakis for graduating in December 2020!    

Welcome to our new graduate student, Jayata Mawani, spring of 2021!

Congratulations to graduate student Jeremy Liew for an accepted ASBMB remote presentation for the spring meeting!    

Congratulations to undergraduate Biochemistry Major Catherine Gaitanakis for graduating in December 2020!    

 

Former Lab News:

Congrats to Jess, Andrew, and Reyaz, who contributed to our recently accepted article at BBRC: Structure and function of the two-component flavin-dependent methanesulfinate monooxygenase within bacterial sulfur assimilation    11/2019

Welcome to our new graduate student, Jonathan Webb!    fall 2019

Courtney and Israa presented research posters at the 2019 ABRCAMS November meeting.

Congratulations to Jess for passing her Master's Defense and beginning her Ph.D. studies at UCLA!    8/2019

Congratulations to Andrew on passing his OQE and entering doctoral candidacy!    8/15/2018

Jess will be presenting a research poster at the 2018 August ACS meeting in Boston next week.

Congratulations to our graduating seniors (2018): MacKenzie Patterson (attanding Brandeis in the fall), Mark MacRae (attending NYU at the Sackler Institute in the fall), and Viet Dieu (entering the College of Podiatric Medicine and Surgery at Des Moines University in fall)

Congratulations to Andrew on completing his written qualifying exams!

Congratulations to Bryan Henriquez on his acceptance into medical school for fall 2018!

Congratulations to our graduating seniors (2017): Susana Ruiz, Sarah Nzikoba, Bryan Henriquez and Andy Pham!

Congratulations to our former lab member, Dhruval Amin, for his acceptance into medical school!

11/25/2016: Congratulations to Yuan Xia on defending her Master's Thesis!

Congratulations to Sam on his acceptance to medical school!

Congratulations to Dhru on his acceptance to a Masters Program!

We wish the best of luck to John, Sam and Dhru as they graduate this May 2016!!!

Congratulations to John on his acceptance to medical school!